I submitted my last post without finishing the list.
Here is the continuation:
epinephrine
* Studies on animals show adverse effect and toxicity on fetus.
* No adequate and well controlled studies done on pregnant women.
* Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
# Teratogenic (capable of causing developmental abnormalities) in some animals.
# No well controlled human data but suggested possible association with eye, ear, digital defects and club foot during first trimester exposure, and with musculoskeletal defects and umbilical hernia during exposure anytime during pregnancy.
# It may cause uterine vessels spasm and potentiate the effects of oxytoxic drugs on the uterus resulting in fetal hypoxia and bradycardia.
morphine
* Studies on animals show adverse effect and toxicity on fetus.
* No adequate and well controlled studies done on pregnant women.
* Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
* Crosses human placenta rapidly.
* No adequate data in first trimester exposure but reported association with inguinal hernia after anytime use during pregnancy.
* Chronic maternal use of the drug causes neonatal withdrawal and respiratory depression.
So, the things that stick out about this information to me are:
-in every case "no adequate and well controlled studies [have been] done on pregnant women"
-almost every item has been found to have adverse effects and toxicity to the fetus in animals
-the reason why the narcotics are given is to make the effects of the drug last longer, otherwise there would be little point in going through the trouble of putting the needle in if the drugs would not hold for the length of the labor or c-section
-the drugs all pass the placenta and in the case of morphine it does so "rapidly" (as I had heard several people argue that "oh, these drugs only effect you--they don't ever get to the baby")
-and something I may or may have not mentioned is that right now at 7 months pregnant I'm allowed to take up to two panadol "safely" for any pain I have (and I've had some really serious back pain this time--that renders me incapable of working some days) and the doctor will continue to tell me that this is the appropriate dosage of pain medicine. I asked if I might use a topical pain reliever called voltaren which is simply a cream that is applied to the skin that many people use for arthritis pain or cramps. I was told strictly that this could be harmful to the baby and I should not do it. This is a rather "weak" topical treatment compared with an epidural. Yet, if I go to the hospital and I'm in labor, the thing that was deemed "harmful to the baby" the day before all of a sudden is administered without any reference to the possible risks. To me, that seems very unbalanced. I wonder if you ask most pregnant women, "So, what exactly is in an epidural and what are the potential side-effects and risks to mother and baby? Did your doctor go over this with you?"--how many women could say, "Yes, I was informed about this by my doctor" unless the woman herself was very proactive and asked the doctor and then hounded him for specific information. Maybe I'm completely wrong and doctors here and elsewhere do a great job of informing their patients of the risks.
In an unrelated thought--it is similar with birth control pills which carry an increased risk for blood clotting problems. I was never informed of this when I was prescribed the medication and not only that the doctor didn't even ask about my family history to see if I was at risk for this (which I am--my maternal grandmother had blood clotting problems and died of a blood clot and my mother has also had issues in the past). Eventually I started having chest pains and problems and only then discovered the risk I was taking with "the pill." I wonder how many other women experience this sort of situation.
Here is the continuation:
epinephrine
* Studies on animals show adverse effect and toxicity on fetus.
* No adequate and well controlled studies done on pregnant women.
* Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
# Teratogenic (capable of causing developmental abnormalities) in some animals.
# No well controlled human data but suggested possible association with eye, ear, digital defects and club foot during first trimester exposure, and with musculoskeletal defects and umbilical hernia during exposure anytime during pregnancy.
# It may cause uterine vessels spasm and potentiate the effects of oxytoxic drugs on the uterus resulting in fetal hypoxia and bradycardia.
morphine
* Studies on animals show adverse effect and toxicity on fetus.
* No adequate and well controlled studies done on pregnant women.
* Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
* Crosses human placenta rapidly.
* No adequate data in first trimester exposure but reported association with inguinal hernia after anytime use during pregnancy.
* Chronic maternal use of the drug causes neonatal withdrawal and respiratory depression.
So, the things that stick out about this information to me are:
-in every case "no adequate and well controlled studies [have been] done on pregnant women"
-almost every item has been found to have adverse effects and toxicity to the fetus in animals
-the reason why the narcotics are given is to make the effects of the drug last longer, otherwise there would be little point in going through the trouble of putting the needle in if the drugs would not hold for the length of the labor or c-section
-the drugs all pass the placenta and in the case of morphine it does so "rapidly" (as I had heard several people argue that "oh, these drugs only effect you--they don't ever get to the baby")
-and something I may or may have not mentioned is that right now at 7 months pregnant I'm allowed to take up to two panadol "safely" for any pain I have (and I've had some really serious back pain this time--that renders me incapable of working some days) and the doctor will continue to tell me that this is the appropriate dosage of pain medicine. I asked if I might use a topical pain reliever called voltaren which is simply a cream that is applied to the skin that many people use for arthritis pain or cramps. I was told strictly that this could be harmful to the baby and I should not do it. This is a rather "weak" topical treatment compared with an epidural. Yet, if I go to the hospital and I'm in labor, the thing that was deemed "harmful to the baby" the day before all of a sudden is administered without any reference to the possible risks. To me, that seems very unbalanced. I wonder if you ask most pregnant women, "So, what exactly is in an epidural and what are the potential side-effects and risks to mother and baby? Did your doctor go over this with you?"--how many women could say, "Yes, I was informed about this by my doctor" unless the woman herself was very proactive and asked the doctor and then hounded him for specific information. Maybe I'm completely wrong and doctors here and elsewhere do a great job of informing their patients of the risks.
In an unrelated thought--it is similar with birth control pills which carry an increased risk for blood clotting problems. I was never informed of this when I was prescribed the medication and not only that the doctor didn't even ask about my family history to see if I was at risk for this (which I am--my maternal grandmother had blood clotting problems and died of a blood clot and my mother has also had issues in the past). Eventually I started having chest pains and problems and only then discovered the risk I was taking with "the pill." I wonder how many other women experience this sort of situation.