Most of the liquid ones, I just store in the fridge - although I know that places like the pharmacies and the Drs office just store them at room temp. For tablets/creams (which are more adult stuff rather than kid stuff) I store at room temp. Inside isn't as bad as out anyway as we run the AC when it's warm. One problem though is that our daughter (19 months) can open the fridge so it's not very "child safe". I probably should get one of those boxes that are hard to open and put them in that... At least with our room temp medicines, they're out of reach... Back home in Australia, we always just stored everything in the cupboard unless it specifically says it should be refrigerated...