Hi Leslie
I think if it's a cough medicine, it's not worth the fight. It would be nice if they would take it, but it doesn't really cure the cough - just soothes a bit. There are some nice-tasting homeopathic cough medicines (there's a Nelson's one at Bumps to Babes that tastes of honey) - so maybe you could try with something like that. Put a bit on a spoon and let your little one dip a finger in and try it. Or put a spoonful in a cup and add 50 ml of warm water to make a soothing drink. But unless she cooperates, you don't have much hope of success.
When it's something important like an antibiotic, then you sometimes just have to be forceful (pin the child down and do the syringe in the cheek squirt). My eldest is now 6 - between the ages of 12 mths (when he learned to spit out) and 5.5yrs, he never willingly took medicine. For fevers, we resorted to paracetamol suppositories (usually inserted while he was asleep!) For bad colds, we could hide Polaramine in Ribena (as it doesn't have much flavour and it's only a 1.25ml dose). For de-worming tablets, we could crush them up and hide them in chocolate icecream or even in cheesy baked beans!
Yet a few months ago, he surprised us. He had to take a foul-tasting antibiotic, very bitter, the taste couldn't be hidden in anything. We reasoned, explained, threatened, begged, bribed... and eventually he agreed to take a syringe of it every night, swiftly followed by gummy bears and cuddles. I would sit on the kitchen floor with him for 20 to 30 minutes talking it through, while he plucked up courage to swallow it. It was a huge leap forward for him - we thought we'd never see the day.
So eventually, no matter how stubborn and strong-willed, your child will reach an age where medicine makes sense ("you won't get better unless you take it"). We still have the battle with our 4-yr-old; whereas the 17mth-old is at the age where we just hold him tight, and syringe it in the back of his cheek. Different stages for different ages.
Good luck!